One Health initiative in the Bolivian Altiplano human fascioliasis hyperendemic area: Lymnaeid biology, population dynamics, microecology and climatic factor influences

Abstract Fascioliasis is a freshwater snail-borne zoonotic disease. The Northern Bolivian Altiplano very high altitude endemic area where the highest human prevalences and intensities have been reported. Preventive chemotherapy by treatment campaigns yearly applied. However, liver fluke infection of cattle, sheep, pigs donkeys assures endemicity consequent re-infection risks. A One Health action has therefore implemented. Activity concerns lymnaeid vectors environment diversity. Studies included growth, egg-laying life span in laboratory-reared lymnaeids. Different habitat types influencing factors were assessed. All populations proved to belong Galba truncatula rDNA sequencing. Analyses comprised physico-chemical characteristics monthly follow-up water temperature, pH quantity, abundance density. Population dynamics transmission foci differed. Mean environmental temperature was lower than development minimum threshold, but higher, except during winter. two generations/year pattern appeared permanent habitats, one generation/year habitats drying out for months. multidisciplinary control measures can be extended from part another. These studies, made first time at altitude, constitute baseline useful fascioliasis other countries.